Journal article

Combining genetic and behavioral predictors of 11-year language outcome

L Gasparini, DA Shepherd, K Lange, J Wang, E Verhoef, EL Bavin, S Reilly, B St. Pourcain, M Wake, AT Morgan

Psychiatry Research | Elsevier BV | Published : 2025

Open access

Abstract

Background: Rapid population-level identification of language disorders could help provide care to young children to improve their outcomes. Two previous studies identified and replicated up to six parent-reported items that predicted 11-year language outcome with ≥71 % sensitivity and specificity. Here, we assess whether including genetic propensity for toddlerhood vocabulary improves predictive accuracy. Method: The Early Language in Victoria Study (ELVS) recruited 1910 8-month-olds in Melbourne in 2003–2004. The Longitudinal Study of Australian Children (LSAC) recruited 5107 0–1-year-olds across Australia in 2004. Both collected parent-reported items at 2–3 years, a comparable 11-year lan..

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